Kit S Lam Selected Research

Ligands

1/2020	Rapid endothelialization of small diameter vascular grafts by a bioactive integrin-binding ligand specifically targeting endothelial progenitor cells and endothelial cells.
10/2019	High-affinity peptide ligand LXY30 for targeting α3β1 integrin in non-small cell lung cancer.
9/2019	One-bead one-compound combinatorial library derived targeting ligands for detection and treatment of oral squamous cancer.
7/2019	Correction to: High-affinity peptide ligand LXY30 for targeting α3β1 integrin in non-small cell lung cancer.
7/2018	Identification of integrin drug targets for 17 solid tumor types.
1/2017	Tumor-targeting peptides from combinatorial libraries.
12/2016	Discovery and characterization of a high-affinity and high-specificity peptide ligand LXY30 for in vivo targeting of α3 integrin-expressing human tumors.
10/2016	Novel theranostic nanoporphyrins for photodynamic diagnosis and trimodal therapy for bladder cancer.
1/2015	Design, synthesis, and application of OB2C combinatorial peptide and peptidomimetic libraries.
10/2013	Telodendrimer-based nanocarriers for the treatment of ovarian cancer.

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Kit S Lam Research Topics

Disease

92	Neoplasms (Cancer) 01/2022 - 01/2002
21	Breast Neoplasms (Breast Cancer) 01/2021 - 09/2003
14	Lymphoma (Lymphomas) 01/2015 - 09/2003
13	Ovarian Neoplasms (Ovarian Cancer) 10/2017 - 05/2005
11	Neoplasm Metastasis (Metastasis) 11/2019 - 11/2006
9	Prostatic Neoplasms (Prostate Cancer) 01/2018 - 11/2006
8	Glioblastoma (Glioblastoma Multiforme) 01/2022 - 05/2005
8	B-Cell Lymphoma (Lymphoma, B Cell) 05/2018 - 09/2007
7	Inflammation (Inflammations) 01/2022 - 01/2006
7	Biliary Liver Cirrhosis (Primary Biliary Cirrhosis) 09/2013 - 05/2003
6	Leukemia 01/2019 - 01/2006
6	Urinary Bladder Neoplasms (Bladder Cancer) 01/2018 - 01/2012
4	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 10/2021 - 08/2015
4	Lung Neoplasms (Lung Cancer) 11/2018 - 09/2007
4	Alzheimer Disease (Alzheimer's Disease) 02/2011 - 01/2007
3	Carcinoma (Carcinomatosis) 01/2021 - 01/2007
3	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 01/2019 - 10/2012
3	Cardiotoxicity 05/2018 - 10/2011
3	Autoimmune Diseases (Autoimmune Disease) 02/2008 - 01/2006
2	Triple Negative Breast Neoplasms 01/2021 - 10/2019
2	Brain Neoplasms (Brain Tumor) 04/2020 - 01/2019
2	Squamous Cell Carcinoma (Epidermoid Carcinoma) 10/2019 - 12/2012
2	Mouth Neoplasms (Oral Cancer) 09/2019 - 11/2018
2	Carcinogenesis 12/2012 - 11/2012
2	Melanoma (Melanoma, Malignant) 09/2011 - 10/2010

Drug/Important Bio-Agent (IBA)

36	Pharmaceutical PreparationsIBA 10/2021 - 01/2002
35	Peptides (Polypeptides)IBA 01/2022 - 01/2002
28	LigandsIBA 01/2020 - 09/2003
19	IntegrinsIBA 01/2021 - 05/2005
19	MicellesIBA 01/2021 - 06/2010
11	Paclitaxel (Taxol)FDA LinkGeneric 01/2021 - 10/2009
9	Proteins (Proteins, Gene)FDA Link 01/2019 - 01/2007
8	Cyclic PeptidesIBA 10/2019 - 10/2005
8	PeptidomimeticsIBA 01/2015 - 01/2006
7	Cell Surface ReceptorsIBA 01/2021 - 01/2002
7	DisulfidesIBA 01/2019 - 09/2011
6	AcidsIBA 04/2020 - 09/2003
6	Doxorubicin (Adriamycin)FDA LinkGeneric 01/2019 - 10/2011
6	Integrin alpha4beta1 (VLA-4)IBA 05/2012 - 07/2006
5	Biomarkers (Surrogate Marker)IBA 09/2019 - 07/2006
5	Peptide LibraryIBA 09/2019 - 09/2007
5	Polysaccharides (Glycans)IBA 02/2014 - 07/2006
5	Integrin alpha3IBA 11/2009 - 05/2005
5	AntibodiesIBA 01/2009 - 01/2002
5	Monoclonal AntibodiesIBA 06/2008 - 01/2002
4	Amyloid beta-PeptidesIBA 10/2021 - 01/2007
4	CY5.5 cyanine dyeIBA 10/2019 - 10/2005
4	EnzymesIBA 10/2011 - 01/2007
3	StreptavidinIBA 10/2019 - 10/2005
3	DNA (Deoxyribonucleic Acid)IBA 10/2019 - 12/2008
3	Daunorubicin (Cerubidine)FDA LinkGeneric 01/2019 - 10/2012
3	Conditioned Culture MediaIBA 01/2019 - 07/2006
3	Acetylcysteine (Siran)FDA LinkGeneric 05/2018 - 09/2011
3	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2018 - 01/2016
3	Amino Acids FDA Link 03/2017 - 11/2006
3	Polyethylene Glycols (Polyethylene Glycol)FDA LinkGeneric 10/2016 - 04/2009
3	Immunoconjugates (Immunoconjugate)IBA 01/2016 - 01/2007
3	AutoantibodiesIBA 09/2013 - 08/2007
3	Tenecteplase FDA Link 01/2009 - 01/2007
3	Glycoproteins (Glycoprotein)IBA 09/2008 - 07/2006
3	Radioisotopes (Radionuclides)IBA 09/2008 - 09/2007
3	XenobioticsIBA 08/2007 - 05/2004
3	AutoantigensIBA 05/2005 - 05/2003
2	Extracellular Matrix ProteinsIBA 04/2020 - 11/2006
2	HydrogelsIBA 01/2020 - 01/2020
2	PolymersIBA 01/2020 - 09/2003
2	Biological ProductsIBA 01/2020 - 01/2012
2	Galectin 1 (LGALS1)IBA 11/2019 - 01/2018
2	RNA (Ribonucleic Acid)IBA 11/2019 - 05/2017
2	1-nitrohydroxyphenyl-N-benzoylalanine (GAL 1)IBA 11/2019 - 01/2018
2	Biotin (Vitamin H)FDA Link 10/2019 - 10/2005
2	Cholic AcidIBA 01/2019 - 10/2016
2	Drug CombinationsIBA 12/2018 - 05/2017
2	osimertinibIBA 11/2018 - 01/2018
2	AndrogensIBA 01/2018 - 01/2010
2	Docetaxel (Taxotere)FDA Link 01/2018 - 06/2017
2	Coloring Agents (Dyes)IBA 10/2017 - 06/2012
2	SolutionsIBA 05/2017 - 10/2016
2	MicroRNAs (MicroRNA)IBA 05/2017 - 11/2012
2	Androgen Receptors (Androgen Receptor)IBA 01/2016 - 01/2016
2	Transcription Factors (Transcription Factor)IBA 04/2015 - 09/2011
2	Secretory Phospholipases A2IBA 01/2015 - 01/2013
2	Caspase 3 (Caspase-3)IBA 01/2015 - 01/2014
2	Alanine (L-Alanine)FDA Link 09/2013 - 11/2006
2	matrigelIBA 12/2012 - 09/2010
2	Fluorescent Dyes (Fluorescent Probes)IBA 09/2012 - 07/2006
2	Reducing AgentsIBA 06/2012 - 09/2011
2	cremophor ELIBA 01/2012 - 06/2010

Therapy/Procedure

39	Therapeutics 10/2021 - 09/2004
12	Drug Therapy (Chemotherapy) 01/2021 - 12/2008
6	Precision Medicine 01/2020 - 01/2012
4	Radioimmunotherapy 01/2022 - 01/2007
4	Lasers (Laser) 01/2021 - 01/2015
3	Radiotherapy 01/2022 - 01/2019
3	Intravenous Injections 01/2021 - 10/2005
3	Immunotherapy 01/2020 - 09/2007
3	Photochemotherapy (Photodynamic Therapy) 01/2018 - 01/2016
3	Castration 01/2018 - 01/2016
2	Phototherapy (Light Therapy) 01/2020 - 01/2016
2	Microbubbles 01/2018 - 07/2012